People
reuben-shaw

Reuben Shaw

Professor
William R. Brody Chair

Reuben grew up in rural upstate New York, went to Cornell for undergraduate school where he did his thesis work with Rick Cerione. He then went to MIT for graduate school and did his PhD work in Tyler Jacks’ lab at the MIT Cancer Center where he focused on neurofibromatosis. Reuben did his postdoctoral work across the river at Harvard Medical School with Lew Cantley. The rest is in the screenplay.
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Sara Campbell

Research Administrative Assistant

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Lillian Eichner

Sr. Research Associate

Lilly obtained her bachelor’s degree in Chemistry from Northwestern University in Illinois, after which she worked as a research associate at the Institute for Systems Biology back in her hometown, Seattle. She received her Ph.D. from McGill University in Montréal, Canada, where she studied the role of the PGC-1/Estrogen-Related Receptor pathway in the regulation of cancer metabolism in the lab of Dr. Vincent Giguère. She continues to study cancer metabolism, and its intersection with epigenetic modifiers, as a post-doc in the Shaw lab.
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Angela Ianniciello

Postdoctoral Fellow

Angela obtained her Bachelor’s degree from the University of Florence, Italy, in Medical Biotechnology. She then moved to the University of Bordeaux, France, to complete her Master’s project where she worked on leukemic stem cells and autophagy. After that, she joined the Helgason lab at the University of Glasgow in Scotland, where she got her PhD. This enabled her to pursue her interest in ULK1, which is a seine-threonine that initiates autophagy and its role in regulating cancer stem cells, metabolism and differentiation. In the Shaw lab she will continue to investigate the link between cancer-cell metabolic adaptation and ULK1.
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Brittany Ellis Jewell

Postdoctoral Fellow

Brittany grew up in Houston, Texas and attended Baylor University where she earned her Bachelor of Science in Biology with minors in Chemistry and Medical Humanities. She then obtained her PhD from the University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences in the lab of Dung-Fang Lee, where she focused on dysregulated oxidative phosphorylation in pediatric osteosarcomagenesis using novel iPSC models. Brittany joined the Shaw lab in March 2021, where she studies the role of AMPK in colorectal cancer formation and persistence and how to target AMPK as a potential new means for treatment.

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Nazma Malik

Postdoctoral Fellow

Nazma grew up in Durham in the North East of England, where she initially studied Medicine (MBBS) for 3 years but later decided to complete her undergraduate as a BSc(Hons) in Biology. She subsequently did a Masters in Research (MRes) in Medical and Molecular Biosciences at the University of Newcastle, UK, followed by a PhD in Biochemistry in the laboratory of Prof Dario Alessi at the MRC PPU in Dundee, UK. Her PhD work was focused on understanding the regulation and function of the SGK3 kinase, a component of the PI3K signaling network. After completion of her PhD, she joined the Shaw lab as a postdoc in early 2018 to study AMPK signalling.
Jan Pencik

Jan Pencik

Postdoctoral Fellow

Jan Pencik is originally from Brno, Czech Republic (the city, where Gregor Mendel, the father of modern genetics, invented his famous Mendelian’s laws). Jan completed his B.S. and M.Sc. in Biochemistry at Palacky University in Olomouc, Czech Republic. Right after graduation, he joined the lab of Prof. Stephan Nussberger, Stuttgart, Germany to study mitochondrial proteins and their cellular signaling networks. He received his Ph.D. from Medical University of Vienna, Austria in the lab of Prof. Lukas Kenner. His graduate work was focused on a novel role of IL-6/STAT3 signaling in regulating senescence, cancer and metastatic progression in prostate cancer. Jan joined the Shaw lab in January 2019 and his current work explores the biochemical aspects of LKB1 and autophagy signaling in cancer immunotherapy.

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Elijah Trefts

Postdoctoral Fellow

Elijah grew up in Maine and completed his B.S. in Biochemistry at Northeastern University in Boston, Massachusetts. He went on to work as a Research Associate at Brigham & Women’s Hospital in the lab of Dr. Luminita Pojoga elucidating signaling mechanisms related to salt-sensitive hypertension. He received his Ph.D. from Vanderbilt University in the lab of Dr. David Wasserman. His graduate work utilized in vivo metabolic flux techniques to discern connections between ECM-integrin signaling and metabolic physiology. Elijah Joined the Shaw lab in May of 2019. His current work focuses on mechanisms linking AMPK to mitochondrial biology as a means to understand the metabolic underpinnings of obesity, cancer, and aging.
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Shira Yomtoubian

Postdoctoral Fellow

Shira obtained her bachelor’s degree in Biological Sciences from the University of Southern California. It was at USC that she also studied accounting and cinematic arts. During her master’s at the University of Minnesota, she worked in the lab of Dr. Colin Campbell studying the molecular origins of hyper-susceptibility to DNA alkylating agents observed in Fanconi Anemia. She then received her PhD from Weill Cornell Graduate School in New York City where she studied the role of epigenetic regulator, EZH2, on metastasis in triple negative breast cancer in the lab of Dr. Vivek Mittal. In the Shaw lab, her work explores the metabolic states that regulate the cancer epigenome.
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Debbie Ross

Research Assistant

The Mouse Whisperer
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TJ Rymoff

Research Assistant

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Liliana (Lili) Vera

Research Assistant / Lab Manager

Hoda-Ahmed

Hoda Ahmed

Graduate Student

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Joshua Baumgart

Graduate Student

Josh grew up in Southern Oregon and completed his B.S. in Biochemistry and Biophysics at Oregon State University before beginning a post-baccalaureate fellowship with the National Institutes of Health working to identify novel therapeutics for Pediatric Sarcomas in the lab of Dr. Lee J. Helman. Josh joined the Shaw lab in June 2018 and is currently working towards his PhD in Biomedical Sciences working to further characterize the tumor suppressor function of LKB1 in the context of lung adenocarcinoma.

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Stephanie Curtis

Graduate Student

Stephanie grew up in San Diego. She completed her B.Sc. in Cell, Molecular, and Developmental Biology at UC Riverside and went on to work at TriLink BioTechnologies in mRNA biology. Stephanie joined the Shaw lab in 2017 and is currently working towards her Ph.D. studying nuclear translocation events driven by changes in cellular energy status.
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Hector Galvez

Graduate Student

Hector received his B.S. in Biological Sciences from California State University, San Marcos. His research focused on characterization of essential genes crucial for the pathogenesis in Ambystoma tigrinum virus. During his time as an undergraduate, he became interested in researching the metabolic changes of cancer, and how they can potentially serve as therapeutic targets. In 2016 he entered the Biological Sciences Ph.D. program at UCSD, and subsequently joined the Shaw lab in early 2017. He studies the role of de novo lipogenesis in cancer.