William R. Brody Chair
Sr. Research Associate
Jan Pencik is originally from Brno, Czech Republic (the city, where Gregor Mendel, the father of modern genetics, invented his famous Mendelian’s laws). Jan completed his B.S. and M.Sc. in Biochemistry at Palacky University in Olomouc, Czech Republic. Right after graduation, he joined the lab of Prof. Stephan Nussberger, Stuttgart, Germany to study mitochondrial proteins and their cellular signaling networks. He received his Ph.D. from Medical University of Vienna, Austria in the lab of Prof. Lukas Kenner. His graduate work was focused on a novel role of IL-6/STAT3 signaling in regulating senescence, cancer and metastatic progression in prostate cancer. Jan joined the Shaw lab in January 2019 and his current work explores the biochemical aspects of LKB1 and autophagy signaling in cancer immunotherapy.